Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548529 | 0.99 | TP53 (0.36) | TP53SMN1; SMN2MAPTRAB9AADORA2A | |
| SCHEMBL11503586 | 0.86 | ALOX15 (0.34) | TP53SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL11553593 | 0.81 | ALDH1A1 (0.45) | TP53SMN1; SMN2MAPTRAB9AADORA2A | |
| SCHEMBL11548968 | 0.81 | MAPT (0.47) | TP53SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL29389523 | 0.78 | TP53 (0.46) | TP53 | |
| SCHEMBL11548259 | 0.78 | NISCH (0.50) | SMN1; SMN2MAPTRAB9ANPC1HSD17B10 | |
| SCHEMBL10453999 | 0.75 | HTR1A (0.39) | RAB9ANPC1TSHRKMT2AALDH1A1 | |
| SCHEMBL10743625 | 0.74 | FTO (0.35) | TP53SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL11465519 | 0.74 | MAPT (0.42) | TP53MAPTRAB9ANPC1MAOB | |
| SCHEMBL11548527 | 0.73 | MAPT (0.41) | TP53MAPTRAB9ANPC1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151180-A | INTERMEDIATES FOR ANTIALLERGENS, ANTIHISTAMINES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-04-24 | — | — | US | disclosed |