Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA3 | P07451 | 4/20 | 0.40 |
| ▸ | CA6 | P23280 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465519 | 0.85 | MAPT (0.42) | CA12CA2CA3CA6CA7 | |
| SCHEMBL11548527 | 0.84 | MAPT (0.41) | CA12CA2CA3CA6CA7 | |
| SCHEMBL11553588 | 0.81 | PTGS1 (0.56) | CA12CA2CA9CA1MAPT | |
| SCHEMBL11018706 | 0.77 | GPR35 (0.58) | MAPTTP53MAOBGPR35NPC1 | |
| SCHEMBL11548964 | 0.76 | MAOB (0.60) | CA12CA2CA3CA6CA7 | |
| SCHEMBL11481868 | 0.76 | TP53 (0.42) | MAPTTP53JMJD6MAOBADORA3 | |
| SCHEMBL11503586 | 0.75 | ALOX15 (0.34) | CA12CA7CA4MAPTTP53 | |
| SCHEMBL10688222 | 0.75 | MAOB (0.49) | MAPTTP53MAOBNPC1KDM4E | |
| SCHEMBL10680122 | 0.73 | PDE3B (0.43) | TP53MAOBMAOAGAPDH | |
| SCHEMBL28577620 | 0.72 | GPR35 (0.62) | MAPTMAOBGPR35POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54059279-A | — | — | None | — | — | JP | disclosed |
| JP-S5459279-A | NOVEL CHROMONE DERIVATIVE AND ITS PREPARATION | TAKEDA CHEM IND LTD | 1979-05-12 | — | — | JP | disclosed |