SCHEMBL11548607

SCHEMBL11548607

CCOC(C)(C)CCCC(C)CCOc1ccc(SC)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.38
LMNA P02545 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
HRH2 P25021 1/20 0.36
HRH1 P35367 1/20 0.36
ALOX5 P09917 4/20 0.34
PPARG P37231 3/20 0.34
PPARA Q07869 3/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
ALDH1A1 P00352 2/20 0.34
PTGES O14684 2/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
MAOB P27338 1/20 0.33
AOC3 Q16853 1/20 0.33
MAPK1 P28482 1/20 0.33
SLC6A4 P31645 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11714406 0.90 FDPS (0.35) LMNAPOLBALOX5PPARGPPARA
SCHEMBL11552255 0.89 SLC6A4 (0.35) ALOX5PPARGPPARAMEN1KMT2A
SCHEMBL11547888 0.88 POLB (0.41) MAPTLMNAKDM4EPOLBMEN1
SCHEMBL11553367 0.87 TDP1 (0.35) MAPTLMNANPSR1KDM4EPOLB
SCHEMBL11548618 0.85 ALOX5 (0.36) LMNAKDM4EPOLBALOX5MEN1
SCHEMBL11553386 0.85 HRH3 (0.40) LMNANPSR1KDM4EPOLBHRH2
SCHEMBL11553217 0.85 LMNA (0.40) MAPTLMNAPOLBALOX5PPARG
SCHEMBL11546267 0.85 MEN1 (0.41) KDM4EPPARGPPARAMEN1KMT2A
SCHEMBL11552460 0.82 MEN1 (0.52) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL11550325 0.82 PPARA (0.44) PPARGPPARAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4137273-A INSECTICIDES, CHEMICAL INTERMEDIATES ZOECON CORPORATION (US) 1979-01-30 US disclosed