Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 6/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11294472 | 0.86 | HDAC4 (0.35) | HDAC4MMP1PDK2CETP | |
| SCHEMBL11544999 | 0.85 | AKR1C1 (0.37) | HDAC4PDK2AKR1C1 | |
| SCHEMBL11542300 | 0.81 | HRH3 (0.33) | HDAC4PDK2CETPSLC6A4SLC6A3 | |
| SCHEMBL11543907 | 0.79 | SLC6A4 (0.38) | SLC6A4SLC6A3 | |
| SCHEMBL11544758 | 0.75 | SLC6A3 (0.42) | SLC6A4SLC6A3 | |
| SCHEMBL11544250 | 0.75 | TAAR1 (0.39) | SLC6A4SLC6A3 | |
| SCHEMBL31452460 | 0.74 | SLC6A4 (0.34) | SLC6A4SLC6A3 | |
| SCHEMBL11472591 | 0.74 | SLC6A4 (0.33) | HDAC4SLC6A4SLC6A3 | |
| SCHEMBL11288858 | 0.74 | SLC6A4 (0.34) | SLC6A4SLC6A3 | |
| SCHEMBL11349725 | 0.73 | ADRB2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | disclosed |