Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 10/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 9/20 | 0.35 |
| ▸ | DRD3 | P35462 | 9/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 7/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548797 | 1.00 | ALOX12 (0.48) | ALOX12DRD2KCNH2POLBSMN1; SMN2 | |
| SCHEMBL4778735 | 0.84 | ALOX12 (0.59) | ALOX12DRD2KCNH2POLBSMN1; SMN2 | |
| SCHEMBL31402597 | 0.78 | ALOX12 (0.56) | ALOX12DRD2KCNH2POLBSMN1; SMN2 | |
| SCHEMBL29561934 | 0.78 | ALOX12 (0.52) | ALOX12DRD2KCNH2POLBSMN1; SMN2 | |
| SCHEMBL29562204 | 0.78 | ALOX12 (0.52) | ALOX12DRD2KCNH2POLBSMN1; SMN2 | |
| SCHEMBL4610933 | 0.78 | ALOX12 (0.56) | ALOX12DRD2KCNH2POLBSMN1; SMN2 | |
| SCHEMBL9277091 | 0.77 | ALOX12 (0.51) | ALOX12DRD2KCNH2POLBSMN1; SMN2 | |
| SCHEMBL27786051 | 0.77 | DRD2 (0.51) | ALOX12DRD2KCNH2POLBSMN1; SMN2 | |
| SCHEMBL11289350 | 0.77 | ALOX12 (0.51) | ALOX12DRD2KCNH2POLBDRD4 | |
| SCHEMBL11281590 | 0.73 | ALOX12 (0.47) | ALOX12DRD2KCNH2POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003771-A1 | Carbostyrile derivatives, their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1979-09-05 | — | — | EP | claimed |