Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | LIG1 | P18858 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11552089 | 0.96 | LMNA (0.47) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL11553065 | 0.94 | MEN1 (0.50) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL11553276 | 0.89 | MAPK1 (0.47) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL11546426 | 0.89 | MAPT (0.42) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL11555138 | 0.89 | MEN1 (0.44) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL11551463 | 0.86 | CNR2 (0.47) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL11547801 | 0.86 | CNR2 (0.47) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL11548819 | 0.85 | ELANE (0.46) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL11550462 | 0.84 | MEN1 (0.42) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL11552923 | 0.84 | LMNA (0.38) | LMNAMAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133814-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |