Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555138 | 0.96 | MEN1 (0.44) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL11547568 | 0.96 | MEN1 (0.47) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL11551278 | 0.89 | ESR1 (0.43) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL11552235 | 0.88 | ALDH1A1 (0.45) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL11549952 | 0.88 | CNR1 (0.43) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL11545551 | 0.85 | MAPK1 (0.45) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL11553065 | 0.84 | MEN1 (0.50) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL11548807 | 0.84 | LMNA (0.46) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL11552880 | 0.83 | ALDH1A1 (0.45) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL11549202 | 0.83 | ALDH1A1 (0.48) | MEN1KMT2AGAARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133814-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |