Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549096 | 0.91 | CNR2 (0.46) | ELANEHSD17B10NPSR1MAPTRAB9A | |
| SCHEMBL11551463 | 0.89 | CNR2 (0.47) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL11547801 | 0.89 | CNR2 (0.47) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL11547389 | 0.89 | ELANE (0.50) | ELANEMEN1KMT2AMAPTLMNA | |
| SCHEMBL11552089 | 0.89 | LMNA (0.47) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL11549453 | 0.86 | ELANE (0.39) | ELANEMEN1KMT2AMAPTLMNA | |
| SCHEMBL11552101 | 0.86 | LMNA (0.41) | HSD17B10NPSR1KMT2AMAPTLMNA | |
| SCHEMBL11551236 | 0.86 | ELANE (0.39) | ELANEMEN1KMT2AMAPTLMNA | |
| SCHEMBL11547983 | 0.85 | SLC22A12 (0.43) | ELANEHSD17B10GFERNPSR1MEN1 | |
| SCHEMBL11553065 | 0.85 | MEN1 (0.50) | MEN1KMT2AMAPTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133814-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |