SCHEMBL11548810

SCHEMBL11548810

O=C1NC(=O)c2c1c1ccc2cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 3/20 0.43
PARP1 P09874 4/20 0.40
ADK P55263 1/20 0.39
PPOX P50336 1/20 0.39
CDK4 P11802 5/20 0.37
CCND1 P24385 5/20 0.37
CCNE2 O96020 3/20 0.37
PRKCA P17252 3/20 0.37
CCNE1 P24864 3/20 0.37
CDK2 P24941 3/20 0.37
CCNB2 O95067 2/20 0.37
PRKCG P05129 2/20 0.37
PRKCB P05771 2/20 0.37
CDK1 P06493 2/20 0.37
CCNB1 P14635 2/20 0.37
CCNB3 Q8WWL7 2/20 0.37
CDK5 Q00535 2/20 0.37
CDK5R1 Q15078 2/20 0.37
MEN1 O00255 1/20 0.37
PRKD3 O94806 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32089673 0.73 GSK3B (0.43) GSK3BPARP1ADKPPOXCDK4
SCHEMBL1081008 0.73 GSK3B (0.43) GSK3BPARP1ADKPPOXCDK4
SCHEMBL2142727 0.70 PARP1 (0.39) GSK3BPARP1PPOXCDK4CCND1
SCHEMBL7429649 0.69 THRB (0.55) GSK3BPARP1PPOXCDK4CCND1
SCHEMBL11518277 0.69 PARP1 (0.43) GSK3BPARP1ADKPPOXCDK4
SCHEMBL28350642 0.69 GSK3B (0.39) GSK3BPARP1ADKPPOXCDK4
SCHEMBL895684 0.69 CES1 (0.56) GSK3BPPOXMEN1MAPTKMT2A
SCHEMBL2292542 0.69 TXNRD1 (0.50) GSK3BPRKCAMEN1MAPTKMT2A
SCHEMBL11519039 0.69 PARP1 (0.44) GSK3BPARP1PPOXCDK4CCND1
SCHEMBL29441220 0.69 PARP1 (0.43) GSK3BPARP1ADKPPOXCDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4143029-A HEXAKIS/ALKOXYMETHYL/MELAMINE, A TRIHYDROCARBYLCARBONYL MELAMINE, AND A BIS/MALEIMIDE UNIROYAL, INC. (US) 1979-03-06 US claimed
CN-113348195-B Resin composition, varnish, laminate, and printed wiring board 普林科技有限公司 2022-05-31 CN disclosed
US-4143029-A HEXAKIS/ALKOXYMETHYL/MELAMINE, A TRIHYDROCARBYLCARBONYL MELAMINE, AND A BIS/MALEIMIDE UNIROYAL, INC. (US) 1979-03-06 US disclosed