Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11551236 | 1.00 | ELANE (0.39) | ELANEMEN1LMNAMAPTRAB9A | |
| SCHEMBL11547555 | 0.92 | PPARG (0.38) | ELANEMAPTCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL11547801 | 0.87 | CNR2 (0.47) | MEN1LMNAMAPTRAB9AKMT2A | |
| SCHEMBL11551463 | 0.87 | CNR2 (0.47) | MEN1LMNAMAPTRAB9AKMT2A | |
| SCHEMBL11552089 | 0.87 | LMNA (0.47) | MEN1LMNAMAPTRAB9AKMT2A | |
| SCHEMBL11548819 | 0.86 | ELANE (0.46) | ELANEMEN1LMNAMAPTRAB9A | |
| SCHEMBL11552101 | 0.84 | LMNA (0.41) | LMNAMAPTRAB9AKMT2ACYP2C9 | |
| SCHEMBL11547256 | 0.84 | MAPT (0.39) | ELANEMEN1MAPTKMT2ACYP2C9 | |
| SCHEMBL11553065 | 0.83 | MEN1 (0.50) | MEN1LMNAMAPTRAB9AKMT2A | |
| SCHEMBL11548807 | 0.83 | LMNA (0.46) | MEN1LMNAMAPTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133814-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |