Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967583 | 0.80 | TSHR (0.48) | HTTALDH1A1TSHRNR4A2 | |
| SCHEMBL27930791 | 0.79 | ALDH1A1 (0.57) | TP53HTTALDH1A1TSHRSLC16A3 | |
| SCHEMBL5455142 | 0.79 | ALDH1A1 (0.61) | TP53HTTALDH1A1TSHRSLC16A3 | |
| SCHEMBL5808173 | 0.79 | TSHR (0.56) | TP53HTTALDH1A1TSHRPOLB | |
| SCHEMBL9422825 | 0.78 | ALDH1A1 (0.44) | TP53HTTALDH1A1TSHRPOLB | |
| SCHEMBL11548850 | 0.75 | ALDH1A1 (0.52) | TP53HTTALDH1A1TSHRPOLB | |
| SCHEMBL8424574 | 0.75 | TSHR (0.56) | TP53HTTALDH1A1TSHRPOLB | |
| SCHEMBL27873445 | 0.74 | TSHR (0.61) | TP53HTTALDH1A1TSHRSLC16A3 | |
| SCHEMBL11758388 | 0.74 | TSHR (0.52) | ALDH1A1TSHRPOLBAKR1B1GAA | |
| SCHEMBL69352 | 0.74 | TSHR (0.68) | TP53HTTALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154745-A | Isobenzofuran route to anthracycloquinones | RESEARCH CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4116981-A | 5,12-EPOXY-NAPHTHACENE-6,11-DIONE DERIVATIVES | Tsay, Yuh-Geng (TW) | 1978-09-26 | — | — | US | disclosed |