Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69352 | 0.88 | TSHR (0.68) | ALDH1A1TP53HTTTSHRFOLH1 | |
| SCHEMBL11327561 | 0.86 | HMGB1 (0.54) | ALDH1A1TP53HTTTSHRMEN1 | |
| SCHEMBL17938486 | 0.86 | TSHR (0.66) | ALDH1A1TP53HTTTSHRFOLH1 | |
| SCHEMBL27930791 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TP53HTTTSHRFOLH1 | |
| SCHEMBL11115984 | 0.85 | FOLH1 (0.61) | ALDH1A1TP53HTTTSHRFOLH1 | |
| SCHEMBL11548850 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TP53HTTTSHRMEN1 | |
| SCHEMBL4351346 | 0.83 | TP53 (0.50) | ALDH1A1TP53HTTTSHRMEN1 | |
| SCHEMBL3461538 | 0.83 | LMNA (0.50) | ALDH1A1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL9396653 | 0.82 | TSHR (0.58) | ALDH1A1TP53HTTTSHRFOLH1 | |
| SCHEMBL10386798 | 0.82 | ALDH1A1 (0.49) | ALDH1A1TP53HTTTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070082922-A1 | Huperzine a prodrugs and uses thereof | PAN BAI-CHUAN | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082922-A1 | Huperzine a prodrugs and uses thereof | APP, ACHE, PSEN1 | ALDH1A1 312/4885TP53 2620/4885HTT 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.