Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547555 | 0.87 | PPARG (0.38) | ELANENPSR1PPARGMAPTPPARA | |
| SCHEMBL11548550 | 0.87 | ALDH1A1 (0.46) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL11547540 | 0.85 | ALDH1A1 (0.43) | ELANEMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11551934 | 0.84 | MAPK1 (0.48) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL11552140 | 0.83 | CNR1 (0.45) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL11548482 | 0.83 | CNR1 (0.45) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL11552086 | 0.82 | LMNA (0.44) | KMT2APPARALMNAMAPK1 | |
| SCHEMBL11550006 | 0.82 | KMT2A (0.45) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL11548419 | 0.81 | MAPK1 (0.50) | KMT2ANPSR1MAPTALDH1A1LMNA | |
| SCHEMBL11549202 | 0.81 | ALDH1A1 (0.48) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133814-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |