Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PGK1 | P00558 | 2/20 | 0.34 |
| ▸ | PGK2 | P07205 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | C1S | P09871 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594495 | 0.83 | TSHR (0.42) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL1203845 | 0.77 | TSHR (0.46) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL11222577 | 0.75 | ACHE (0.48) | ALDH1A1MAPK1TDP1HPGDACHE | |
| SCHEMBL6671376 | 0.74 | TSHR (0.44) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL15147577 | 0.74 | TSHR (0.44) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL5966315 | 0.72 | HPGD (0.59) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL11551263 | 0.72 | ALDH1A1 (0.36) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL14337805 | 0.72 | TSHR (0.48) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL3353801 | 0.72 | PGK1 (0.44) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL29080970 | 0.72 | TSHR (0.42) | TSHRALDH1A1CYP3A4MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104395329-A | Method for producing phosphoric acid ester amides | DAIKYO CHEMICAL CO LTD | 2015-03-04 | — | — | CN | disclosed |
| US-4156663-A | 260/857 R | KANEBO, LTD. (JP) | 1979-05-29 | — | — | US | disclosed |
| US-4072658-A | FLAME RETARDANTS | KANEBO, LTD. (JA) | 1978-02-07 | — | — | US | disclosed |