Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 2/20 | 0.43 |
| ▸ | LDHB | P07195 | 2/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252625 | 0.88 | BCL2L1 (0.47) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL11549646 | 0.80 | MEN1 (0.45) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL27738449 | 0.77 | PTPN1 (0.55) | PTPN1PTPN2PTPN6BCL2BCL2L1 | |
| SCHEMBL3361331 | 0.76 | TSHR (0.57) | ALDH1A1PTPN1PTPN2PTPN6TSHR | |
| SCHEMBL28606647 | 0.76 | MEN1 (0.42) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL3048092 | 0.75 | KDM4E (0.52) | MEN1KMT2AALDH1A1 | |
| SCHEMBL4369651 | 0.75 | PTPN1 (0.49) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL5202410 | 0.74 | BID (0.66) | PTPN1PTPN2PTPN6LDHALDHB | |
| SCHEMBL200212 | 0.74 | TSHR (0.59) | ALDH1A1PTPN1PTPN2PTPN6BCL2L1 | |
| SCHEMBL27407359 | 0.74 | LDHA (0.50) | ALDH1A1MAPTPTPN1PTPN2PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154745-A | Isobenzofuran route to anthracycloquinones | RESEARCH CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4116981-A | 5,12-EPOXY-NAPHTHACENE-6,11-DIONE DERIVATIVES | Tsay, Yuh-Geng (TW) | 1978-09-26 | — | — | US | disclosed |