SCHEMBL200212

SCHEMBL200212

O=C(O)c1cccc(Cc2ccccc2)c1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.59
FOLH1 Q04609 4/20 0.53
PTPN1 P18031 5/20 0.53
PTPN2 P17706 1/20 0.51
PTPN6 P29350 1/20 0.51
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
AKR1C3 P42330 1/20 0.47
ALDH1A1 P00352 1/20 0.46
ALOX15 P16050 1/20 0.46
HNF4A P41235 1/20 0.46
BID P55957 1/20 0.45
BCL2L1 Q07817 1/20 0.45
MCL1 Q07820 1/20 0.45
BAK1 Q16611 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL343520 0.98 TSHR (0.57) TSHRFOLH1PTPN1PTPN2PTPN6
SCHEMBL29367715 0.88 FOLH1 (0.50) TSHRFOLH1PTPN1PTPN2PTPN6
SCHEMBL23708 0.88 FOLH1 (0.50) TSHRFOLH1PTPN1PTPN2PTPN6
SCHEMBL31090800 0.88 FOLH1 (0.50) TSHRFOLH1PTPN1PTPN2PTPN6
SCHEMBL10483666 0.87 TSHR (0.56) TSHRFOLH1PTPN1PTPN2PTPN6
SCHEMBL5553275 0.86 FOLH1 (0.49) TSHRFOLH1PTPN1PTPN2PTPN6
SCHEMBL30232852 0.85 ALDH1A1 (0.70) TSHRFOLH1PTPN1ALDH1A1
SCHEMBL4010440 0.85 TSHR (0.47) TSHRFOLH1PTPN1PTPN2PTPN6
SCHEMBL7201768 0.84 HTT (0.53) TSHRFOLH1AKR1C3ALDH1A1ALOX15
SCHEMBL23003 0.84 TSHR (0.79) TSHRFOLH1PTPN1PTPN2PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111205808-A Boiling-resistant solvent-free polyurethane adhesive and preparation method thereof 广东新辉化学有限公司 2020-05-29 CN claimed
EP-3207022-B1 REDUCING POLYMER FOULING AND AGGLOMERATION IN ACRYLATE/METHACRYLATE PROCESSES ECOLAB USA INC (US) 2020-01-29 EP claimed
EP-3328930-B1 METHOD TO ADDITIVE MANUFACTURE BIOCOMPATIBLE MATERIAL AND ARTICLES MADE BY THE METHOD DOW GLOBAL TECHNOLOGIES LLC (US) 2019-05-29 EP claimed
EP-1877512-B1 METHOD FOR IMPROVING ACOUSTIC PROPERTIES FERRO BELGIUM SPRL (BE) 2016-10-12 EP claimed
EP-1824460-B1 A STABILIZED POLYMERIC DELIVERY SYSTEM TOLMAR THERAPEUTICS INC (US) 2014-12-24 EP claimed
US-20090130316-A1 Method For Improving Accoustic Properties FERRO (BELGIUM) S.P.R.L. (BE) 2009-05-21 US claimed
EP-1637322-B1 Method for manufacturing a flexographic printing master AGFA GRAPHICS NV (BE) 2009-05-13 EP claimed
US-20080299168-A1 Stabilized Polymeric Delivery System WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2008-12-04 US claimed
CN-101296801-A Image recording medium and image layer HEWLETT PACKARD DEVELOPMENT CO (US) 2008-10-29 CN claimed
EP-1940629-A1 IMAGE RECORDING MEDIA AND IMAGE LAYERS Hewlett-Packard Development Company, L.P. (US) 2008-07-09 EP claimed
EP-0799418-B1 A CARBON DIOXIDE SENSITIVE MATERIAL SEALED AIR NZ LTD (NZ) 1999-05-26 EP claimed
EP-0741046-B1 A thermal sensitive recording sheet JUJO PAPER CO LTD (JP) 1999-03-31 EP claimed
US-5792469-A Biodegradable in situ forming film dressing ATRIX LABORATORIES, INC. (US) 1998-08-11 US claimed
EP-0494169-B1 Process for the preparation of charged thermosetting polyurethane compositions and homogeneous and stable suspensions of the charge JAYMO S N C (FR) 1996-11-13 EP claimed
US-5525262-A CAULKING MATERIAL COMPRISING HOLLOW SPHERES OF REFRACTORIES HAVING SURFACE SPUTTER DEPOSITED ELECTROCONDUCTIVE METALS AND METAL NITRIDES, LIQUID CURABLE POLYETHERS OR POLYTHIOETHER; COLD TEMPERATURE SETTING RESINS NORTHROP GRUMMAN CORPORATION (US) 1996-06-11 US claimed
US-5429772-A Electroconductive fillers of hollow spheres and layers NORTHROP GRUMMAN CORPORATION (US) 1995-07-04 US claimed
US-5238969-A PROCESS FOR THE PREPARATION OF CHARGED THERMOSETTING COMPOUNDS OF THE POLYURETHANE TYPE AND COMPOUNDS OBTAINED THEREBY OMYA S.A. (FR) 1993-08-24 US claimed
EP-0494169-A1 PROCESS FOR THE PREPARATION OF CHARGED THERMOSETTING COMPOUNDS OF THE POLYURETHANE TYPE AND COMPOUNDS OBTAINED THEREBY. EXXON CHEMICAL PATENTS INC (US) 1992-07-15 EP claimed
WO-1991003513-A1 PROCESS FOR THE PREPARATION OF CHARGED THERMOSETTING COMPOUNDS OF THE POLYURETHANE TYPE AND COMPOUNDS OBTAINED THEREBY EXXON CHEMICAL PATENTS INC. (US) 1991-03-21 WO claimed
EP-0005921-B1 MARK-RECORDING SYSTEMS MONSANTO EUROPE S.A./N.V. (BE) 1982-10-27 EP claimed