Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
| ▸ | BID | P55957 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | LDHB | P07195 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503737 | 0.89 | MMP2 (0.44) | ALDH1A1GAAMAPTBCL2L1BID | |
| SCHEMBL17228259 | 0.81 | BCL2 (0.51) | MEN1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL200212 | 0.80 | TSHR (0.59) | ALDH1A1TSHRBCL2L1BIDMCL1 | |
| SCHEMBL11549062 | 0.80 | MEN1 (0.46) | MEN1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL5202410 | 0.80 | BID (0.66) | BCL2L1BIDMCL1BAK1PTPN1 | |
| SCHEMBL8477665 | 0.79 | MMP2 (0.42) | LMNAGAABCL2L1BIDMCL1 | |
| SCHEMBL8477659 | 0.79 | MMP2 (0.42) | GAAMAPTBCL2L1BIDMCL1 | |
| SCHEMBL321003 | 0.79 | GABRA1 (0.45) | ALDH1A1GAAMAPTBCL2L1BID | |
| SCHEMBL343520 | 0.79 | TSHR (0.57) | ALDH1A1TSHRBCL2L1BIDMCL1 | |
| SCHEMBL11322877 | 0.79 | TSHR (0.45) | MEN1KMT2ATSHRBCL2L1BID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154745-A | Isobenzofuran route to anthracycloquinones | RESEARCH CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4116981-A | 5,12-EPOXY-NAPHTHACENE-6,11-DIONE DERIVATIVES | Tsay, Yuh-Geng (TW) | 1978-09-26 | — | — | US | disclosed |