Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 17/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 17/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PLD2 | O14939 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | C5 | P01031 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546932 | 0.95 | LTA4H (0.54) | PSMB1PSMB5PSMB2ESR1ESR2 | |
| SCHEMBL11551801 | 0.95 | ESR1 (0.59) | PSMB1PSMB5PSMB2ESR1ESR2 | |
| SCHEMBL11551657 | 0.92 | ESR1 (0.50) | PSMB1PSMB5PSMB2ESR1ESR2 | |
| SCHEMBL7950100 | 0.92 | ESR1 (0.61) | PSMB1PSMB5PSMB2ESR1ESR2 | |
| SCHEMBL11551921 | 0.91 | ESR1 (0.63) | PSMB1PSMB5PSMB2ESR1ESR2 | |
| SCHEMBL11552007 | 0.89 | KDM4E (0.53) | PSMB1PSMB5PSMB2ESR1ESR2 | |
| SCHEMBL7775848 | 0.89 | ESR1 (0.62) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL11548378 | 0.88 | ESR1 (0.64) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL11551029 | 0.88 | ESR1 (0.66) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL11555041 | 0.88 | ESR1 (0.66) | ESR1ESR2MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133814-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |