Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 15/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 15/20 | 0.51 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.48 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553642 | 0.91 | ESR1 (0.56) | LTA4HESR1ESR2 | |
| SCHEMBL11551657 | 0.91 | ESR1 (0.50) | KDM4ELTA4HESR1ESR2PSMB1 | |
| SCHEMBL11546932 | 0.90 | LTA4H (0.54) | KDM4ELTA4HESR1ESR2PSMB1 | |
| SCHEMBL11549231 | 0.89 | PSMB1 (0.52) | LTA4HESR1ESR2PSMB1PSMB5 | |
| SCHEMBL11551829 | 0.88 | LTA4H (0.60) | KDM4ELTA4HESR1ESR2PSMB1 | |
| SCHEMBL11550799 | 0.88 | LTA4H (0.60) | KDM4ELTA4HESR1ESR2PSMB1 | |
| SCHEMBL11546606 | 0.88 | ESR1 (0.56) | LTA4HESR1ESR2PSMB1PSMB5 | |
| SCHEMBL11549389 | 0.87 | LTA4H (0.61) | KDM4ELTA4HESR1ESR2PSMB1 | |
| SCHEMBL11601598 | 0.87 | KDM4E (0.53) | KDM4ELTA4HESR1ESR2PSMB1 | |
| SCHEMBL7950100 | 0.87 | ESR1 (0.61) | LTA4HESR1ESR2PSMB1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133814-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |