Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549738 | 0.95 | NPC1 (0.51) | NPC1RAB9ARECQLKMT2AMAPT | |
| SCHEMBL11545088 | 0.95 | NPC1 (0.51) | NPC1RAB9ARECQLKMT2AMAPT | |
| SCHEMBL11434337 | 0.92 | NPC1 (0.50) | NPC1RAB9ARECQLKMT2AMAPT | |
| SCHEMBL27395658 | 0.90 | NPC1 (0.47) | NPC1RAB9ARECQLKMT2AMAPT | |
| SCHEMBL11546681 | 0.89 | RECQL (0.49) | NPC1RAB9ARECQLKMT2AMAPT | |
| SCHEMBL8977411 | 0.88 | MAPT (0.47) | NPC1RAB9ARECQLKMT2AMAPT | |
| SCHEMBL27460583 | 0.86 | ALDH1A1 (0.54) | NPC1RAB9ARECQLKMT2AMAPT | |
| SCHEMBL6284658 | 0.82 | HTR1A (0.50) | NPC1RAB9ARECQLKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3092379 | 0.81 | HTR1A (0.49) | NPC1RAB9ARECQLKMT2AMEN1 | |
| SCHEMBL924102 | 0.80 | TDP1 (0.52) | NPC1RAB9ARECQLKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |