Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549738 | 0.92 | NPC1 (0.51) | MAPTRECQLNPC1RAB9ALMNA | |
| SCHEMBL11545088 | 0.89 | NPC1 (0.51) | MAPTRECQLNPC1RAB9ALMNA | |
| SCHEMBL11549296 | 0.88 | NPC1 (0.58) | MAPTRECQLNPC1RAB9ALMNA | |
| SCHEMBL27460583 | 0.84 | ALDH1A1 (0.54) | MAPTRECQLNPC1RAB9ALMNA | |
| SCHEMBL11434337 | 0.84 | NPC1 (0.50) | MAPTRECQLNPC1RAB9ALMNA | |
| SCHEMBL27395658 | 0.82 | NPC1 (0.47) | MAPTRECQLNPC1RAB9ALMNA | |
| SCHEMBL9699807 | 0.81 | ESR1 (0.48) | MAPTRECQLNPC1RAB9ALMNA | |
| SCHEMBL11546681 | 0.81 | RECQL (0.49) | MAPTRECQLNPC1RAB9ALMNA | |
| SCHEMBL248876 | 0.79 | NPC1 (0.53) | MAPTRECQLNPC1RAB9ALMNA | |
| SCHEMBL28471208 | 0.79 | TSHR (0.56) | MAPTNPC1RAB9ALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517871-B1 | NOVEL NITROANILIDES AND THEIR PREPARATION | KODAK LTD (GB) | 1996-04-24 | — | — | EP | disclosed |
| EP-0517871-B1 | NOVEL NITROANILIDES AND THEIR PREPARATION | KODAK LTD (GB) | 1996-04-24 | — | — | EP | disclosed |
| US-5382682-A | Nitroanilides and their preparation | EASTMAN KODAK COMPANY (US) | 1995-01-17 | — | — | US | disclosed |
| US-5382682-A | Nitroanilides and their preparation | EASTMAN KODAK COMPANY (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0517871-A1 | NOVEL NITROANILIDES AND THEIR PREPARATION. | KODAK LTD (GB) | 1992-12-16 | — | — | EP | disclosed |
| EP-0517871-A1 | NOVEL NITROANILIDES AND THEIR PREPARATION. | KODAK LTD (GB) | 1992-12-16 | — | — | EP | disclosed |
| WO-1992011230-A1 | NOVEL NITROANILIDES AND THEIR PREPARATION | KODAK LIMITED (GB) | 1992-07-09 | — | — | WO | disclosed |
| WO-1992011230-A1 | NOVEL NITROANILIDES AND THEIR PREPARATION | KODAK LIMITED (GB) | 1992-07-09 | — | — | WO | disclosed |