Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29448325 | 0.92 | KDM4E (0.62) | KDM4ETDP1HTR2AHTR2CHTR2B | |
| SCHEMBL348813 | 0.92 | KDM4E (0.62) | KDM4ETDP1HTR2AHTR2CHTR2B | |
| SCHEMBL14077416 | 0.85 | KDM4E (0.55) | KDM4ETDP1HTR2AHTR2CHTR2B | |
| SCHEMBL6561661 | 0.84 | KDM4E (0.59) | KDM4ETDP1CYP1A2CYP2A6PTPRC | |
| SCHEMBL5656126 | 0.78 | TDP1 (0.55) | KDM4ETDP1CYP1A2CYP2A6PTPRC | |
| SCHEMBL28234341 | 0.77 | CYP2A6 (0.55) | TDP1HTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL10400505 | 0.76 | HTR2A (0.61) | HTR2AHTR2CHTR2BCYP1A2CYP2A6 | |
| SCHEMBL11273634 | 0.75 | CYP1A2 (0.50) | KDM4ETDP1CYP1A2CYP2A6PTPRC | |
| SCHEMBL1448749 | 0.74 | PTGS1 (0.53) | KDM4ETDP1CYP1A2CYP2A6 | |
| SCHEMBL10418916 | 0.74 | SIGMAR1 (0.54) | HTR2AHTR2CHTR2BCYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4164415-A | Branched alkyl-2-naphthaleneacetic acids as herbicides and insecticide intermediates | AMERICAN CYANAMID CO. (US) | 1979-08-14 | — | — | US | disclosed |
| US-4088782-A | Substituted-benzyl α-C1 -C4 alkyl-2-naphthaleneacetates as insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4046799-A | INSECTICIDES | AMERICAN CYANAMID COMPANY (US) | 1977-09-06 | — | — | US | disclosed |