Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542960 | 0.77 | CRBN (0.33) | CRBNDDB1ALOX5SMN1; SMN2 | |
| SCHEMBL19807936 | 0.74 | SMN1; SMN2 (0.41) | CRBNDDB1ALOX5PDE3BPDE3A | |
| SCHEMBL11545281 | 0.74 | KDM4E (0.41) | CRBNDDB1ALOX5SMN1; SMN2 | |
| SCHEMBL11541426 | 0.72 | PDE3B (0.35) | CRBNDDB1PDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL32688313 | 0.70 | CRBN (0.44) | CRBNDDB1 | |
| SCHEMBL1713613 | 0.70 | CRBN (0.44) | CRBNDDB1 | |
| SCHEMBL11544043 | 0.69 | DAPK3 (0.37) | CRBNDDB1SMN1; SMN2 | |
| SCHEMBL20595719 | 0.69 | CYP1A2 (0.39) | CRBNDDB1 | |
| SCHEMBL11549394 | 0.67 | SCN9A (0.35) | CRBN | |
| SCHEMBL11544625 | 0.66 | MAPT (0.36) | CRBNDDB1ALOX5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167569-A | ANTICOAGULANTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-09-11 | — | — | US | disclosed |