Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030381 | 0.87 | ALDH1A1 (0.72) | SIGMAR1ALDH1A1PKMSMN1; SMN2DRD2 | |
| SCHEMBL6030554 | 0.87 | SIGMAR1 (0.62) | SIGMAR1ALDH1A1PKMSMN1; SMN2DRD2 | |
| SCHEMBL2550544 | 0.86 | TDP1 (0.64) | SIGMAR1ALDH1A1SMN1; SMN2DRD2HSD17B10 | |
| SCHEMBL5542061 | 0.85 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1PKMSMN1; SMN2DRD2 | |
| SCHEMBL5542069 | 0.85 | DRD4 (0.66) | SIGMAR1ALDH1A1PKMSMN1; SMN2DRD2 | |
| Bromide SCHEMBL6579961 | 0.85 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1PKMSMN1; SMN2DRD2 | |
| SCHEMBL28313258 | 0.85 | MAPT (0.68) | SIGMAR1ALDH1A1PKMSMN1; SMN2DRD2 | |
| Bromide SCHEMBL6578060 | 0.85 | ALDH1A1 (0.71) | SIGMAR1ALDH1A1PKMSMN1; SMN2DRD2 | |
| SCHEMBL11923385 | 0.85 | SIGMAR1 (0.79) | SIGMAR1ALDH1A1PKMSMN1; SMN2DRD2 | |
| SCHEMBL11549618 | 0.85 | KDM4E (0.78) | SIGMAR1ALDH1A1SMN1; SMN2DRD2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140775-A | HYPOTENSIVE AGENTS | THE UPJOHN COMPANY (US) | 1979-02-20 | — | — | US | disclosed |