Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550401 | 0.88 | TSHR (0.57) | APEX1NPC1RAB9ATSHREPHX2 | |
| SCHEMBL11548842 | 0.88 | APEX1 (0.46) | APEX1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL11554395 | 0.83 | POLB (0.46) | NPC1RAB9AMAPTSMN1; SMN2POLB | |
| SCHEMBL11553389 | 0.77 | APEX1 (0.52) | APEX1NPC1RAB9ATSHREPHX2 | |
| SCHEMBL4770587 | 0.74 | TSHR (0.68) | APEX1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL11549818 | 0.70 | POLB (0.43) | NPC1RAB9AMAPTSMN1; SMN2TSHR | |
| SCHEMBL11548778 | 0.70 | EPHX2 (0.72) | NPC1RAB9AMAPTSMN1; SMN2EPHX2 | |
| SCHEMBL687878 | 0.67 | TSHR (0.79) | APEX1TSHR | |
| SCHEMBL20741156 | 0.67 | POLB (0.61) | APEX1MAPTTSHRPOLB | |
| SCHEMBL8153658 | 0.66 | HSD17B10 (0.65) | APEX1SMN1; SMN2PNPLA2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4155915-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-05-22 | — | — | US | claimed |