Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | EEF2K | O00418 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ROS1 | P08922 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549604 | 0.88 | APEX1 (0.44) | APEX1PNPLA2HDAC6TSHREPHX2 | |
| SCHEMBL11550401 | 0.87 | TSHR (0.57) | APEX1PNPLA2HDAC6TSHREPHX2 | |
| SCHEMBL11549818 | 0.82 | POLB (0.43) | TSHRTP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11553389 | 0.81 | APEX1 (0.52) | APEX1PNPLA2HDAC6TSHRTP53 | |
| SCHEMBL3423738 | 0.76 | SMN1; SMN2 (0.51) | TSHRTP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11548245 | 0.72 | APEX1 (0.44) | APEX1TSHRTP53EPHX2NPC1 | |
| SCHEMBL13956804 | 0.71 | ALDH1A1 (0.46) | TP53NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11548778 | 0.71 | EPHX2 (0.72) | TP53EPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11554395 | 0.70 | POLB (0.46) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5923355 | 0.70 | RAB9A (0.41) | TSHRNPC1RAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4155915-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-05-22 | — | — | US | claimed |
| US-4155915-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-05-22 | — | — | US | disclosed |