SCHEMBL11549772

SCHEMBL11549772

Cn1c(=S)ccc2cc(Cl)ccc21

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.65
RXFP1 Q9HBX9 2/20 0.65
ALDH1A1 P00352 1/20 0.55
PSMB8 P28062 1/20 0.43
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
CYP2A6 P11509 1/20 0.39
KDM4E B2RXH2 1/20 0.38
HCRTR1 O43613 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
BRPF1 P55201 1/20 0.37
THRB P10828 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
AHR P35869 1/20 0.36
CDK4 P11802 1/20 0.35
CCND1 P24385 1/20 0.35
KMO O15229 1/20 0.35
HTR3A P46098 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31202712 0.77 BRPF1 (0.62) RXFP1BRPF1
SCHEMBL435737 0.72 RXFP1 (0.47) MAPTRXFP1ALDH1A1KDM4ECASP1
SCHEMBL2332129 0.71 MAPT (1.00) MAPTRXFP1ALDH1A1PSMB8HTR2A
SCHEMBL8899119 0.71 RXFP1 (0.46) MAPTRXFP1PSMB8HTR2AHTR2C
SCHEMBL3386079 0.71 RXFP1 (0.46) MAPTRXFP1ALDH1A1PSMB8HTR2A
SCHEMBL1092569 0.69 PRKCI (0.59) HTR2AHTR2CCYP2A6THRBCDK4
SCHEMBL11462221 0.69 PSMB8 (0.52) MAPTRXFP1ALDH1A1PSMB8KDM4E
SCHEMBL17324809 0.69 RXFP1 (0.64) RXFP1ALDH1A1KDM4EMEN1KMT2A
SCHEMBL10222171 0.68 PSMB8 (0.42) MAPTALDH1A1PSMB8HTR2AHTR2C
SCHEMBL7799883 0.68 KMT2A (0.50) RXFP1ALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4144071-A DISPERSION IN HYDROPHILIC COLLOID LAYER OF HYDROQUINONE REDUCING AGENT AND COMPOUND CONTAINING HETEROCYCLICTHIO GROUP FUJI PHOTO FILM CO., LTD. (JP) 1979-03-13 US disclosed
US-3984245-A SILVER HALIDE EMULSION, DEVELOPMENT INHIBITOR, COLLOID, MULTILAYER FUJI PHOTO FILM CO., LTD. (JA) 1976-10-05 US disclosed
US-3961963-A HYDROQUINONE DERIVATIVE, DEVELOPMENT INHIBITOR FUJI PHOTO FILM CO., LTD. (JA) 1976-06-08 US disclosed