SCHEMBL2332129

SCHEMBL2332129

Cn1c(=S)ccc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 1.00
ALDH1A1 P00352 2/20 1.00
CA12 O43570 2/20 0.57
CA9 Q16790 2/20 0.57
BRD4 O60885 1/20 0.57
BRPF1 P55201 1/20 0.57
KAT2B Q92831 1/20 0.57
BRD9 Q9H8M2 1/20 0.57
RXFP1 Q9HBX9 2/20 0.57
CDK4 P11802 4/20 0.45
CCND1 P24385 4/20 0.45
KMT2A Q03164 2/20 0.44
DAO P14920 1/20 0.41
MCL1 Q07820 1/20 0.41
GPR3 P46089 1/20 0.41
PSMB8 P28062 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL865039 0.73 ALDH1A1 (0.57) MAPTALDH1A1CA12CA9BRD4
SCHEMBL4097687 0.73 CA12 (0.57) MAPTALDH1A1CA12CA9BRD4
SCHEMBL248619 0.73 BRPF1 (1.00) MAPTALDH1A1CA12CA9BRD4
SCHEMBL29967380 0.73 BRPF1 (1.00) MAPTALDH1A1CA12CA9BRD4
Hydrochloric Acid SCHEMBL30419636 0.71 BRPF1 (0.96) MAPTALDH1A1CA12CA9BRD4
Hydrochloric Acid SCHEMBL1236989 0.71 BRPF1 (0.96) MAPTALDH1A1CA12CA9BRD4
SCHEMBL11549772 0.71 MAPT (0.65) MAPTALDH1A1BRPF1RXFP1CDK4
SCHEMBL19669320 0.70 ALDH1A1 (0.54) MAPTALDH1A1CA12CA9BRD4
SCHEMBL11377592 0.70 ALDH1A1 (0.53) MAPTALDH1A1RXFP1KMT2AMCL1
Hydrochloric Acid SCHEMBL7218030 0.70 BRPF1 (0.92) MAPTALDH1A1CA12CA9BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5738969-A WATER INSOLUBLE COMPOUND HAVING MERCAPTO OR THIONE GROUP, AND SULFONATED STYRENE-CONTAINING POLYMER MITSUBISHI PAPER MILLS LIMITED (JP) 1998-04-14 US claimed
US-11046889-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2021-06-29 US disclosed
US-10919870-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2021-02-16 US disclosed
US-10649124-B2 Composition including compound having mesogenic group, polymer and optically anisotropic body obtained by polymerizing polymerizable composition, and phase difference film DIC CORPORATION (JP) 2020-05-12 US disclosed
US-20190025490-A1 COMPOSITION INCLUDING COMPOUND HAVING MESOGENIC GROUP, POLYMER AND OPTICALLY ANISOTROPIC BODY OBTAINED BY POLYMERIZING POLYMERIZABLE COMPOSITION, AND PHASE DIFFERENCE FILM DIC CORPORATION (JP) 2019-01-24 US disclosed
EP-3346304-A1 COMPOSITION INCLUDING COMPOUND HAVING MESOGENIC GROUP, POLYMER AND OPTICALLY ANISOTROPIC BODY OBTAINED BY POLYMERIZING POLYMERIZABLE COMPOSITION, AND PHASE DIFFERENCE FILM DIC Corporation (JP) 2018-07-11 EP disclosed
US-20180022716-A1 POLYMERIZABLE COMPOUND AND OPTICAL ISOMER DIC CORPORATION (JP) 2018-01-25 US disclosed
US-20180022716-A1 POLYMERIZABLE COMPOUND AND OPTICAL ISOMER DIC CORPORATION (JP) 2018-01-25 US disclosed
WO-2017079867-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2017-05-18 WO disclosed
CN-105885466-A Synthesis method of monomethine cyanine dye 付义乐 2016-08-24 CN disclosed
US-5738969-A WATER INSOLUBLE COMPOUND HAVING MERCAPTO OR THIONE GROUP, AND SULFONATED STYRENE-CONTAINING POLYMER MITSUBISHI PAPER MILLS LIMITED (JP) 1998-04-14 US disclosed
US-5525455-A IMPROVING INK RECEPTIVITY BY APPLYING SOLUTION CONTAINING COMPOUND HAVING OLEOPHILIC GROUP AND MERCAPTO OR THIONE GROUP, ALKANOLAMINE MITSUBISHI PAPER MILLS LIMITED (JP) 1996-06-11 US disclosed
EP-0639798-A1 Treating solution for lithographic printing plate MITSUBISHI PAPER MILLS, LTD. (JP) 1995-02-22 EP disclosed
US-5391457-A For silver complex diffusion transfer processing in presence of a triazole, oxadiazole type compound; wear resistance of plates; good ink receptivity; free from waste solution disposal FUJI PHOTO FILM CO., LTD (JP) 1995-02-21 US disclosed
EP-0282365-B1 1-DETHIA-2-THIA-CEPHALOSPORANIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS THERAPEUTIC AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1993-05-12 EP disclosed
US-5153097-A LIGHT-SENSITIVE MATERIAL FOR LITHOGRAPHIC PRINTING PLATE AND PROCESS FOR MAKING PRINTING PLATE MITSUBISHI PAPER MILLS LIMITED (JP) 1992-10-06 US disclosed
US-4908359-A Pharmaceuticals Uclaf, Roussel (FR) 1990-03-13 US disclosed
EP-0282365-A1 1-Dethia-2-thia-cephalosporanic-acid derivatives, process for their preparation, their use as therapeutic agents and pharmaceutical compositions containing them ROUSSEL-UCLAF (FR) 1988-09-14 EP disclosed
US-4230792-A COMPLEXING SILVER WITH THIOL OR THIONE MITSUBISHI PAPER MILLS, LTD. (JP) 1980-10-28 US disclosed
US-3954474-A SILVER HALIDE EMULSION; ALDEHYDE TYPE HARDENER FUJI PHOTO FILM CO., LTD. (JA) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919870-B2 Polymerizable compound and optically anisotropic body ZYX, ZW10, DPY30 MAPT 545/4885ALDH1A1 2807/4885CA12 2640/4885
US-20180022716-A1 POLYMERIZABLE COMPOUND AND OPTICAL ISOMER SMC4, MAP1LC3C, ZW10 MAPT 27/4885ALDH1A1 3195/4885CA12 2114/4885
US-11046889-B2 Polymerizable compound and optically anisotropic body OCIAD1, RCC1, OCIAD2 MAPT 323/4885ALDH1A1 217/4885CA12 3107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.