Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL27753947 | 0.99 | ALDH1A1 (0.47) | ALDH1A1POLBKMT2ATLR8HTT | |
| SCHEMBL28768428 | 0.91 | ALDH1A1 (0.54) | ALDH1A1POLBKMT2ATLR8HTT | |
| SCHEMBL949946 | 0.90 | ALDH1A1 (0.56) | ALDH1A1POLBKMT2ATLR8HTT | |
| SCHEMBL1155603 | 0.84 | ALDH1A1 (0.50) | ALDH1A1POLBKMT2ATLR8HTT | |
| Oxalic Acid SCHEMBL1155576 | 0.79 | FDPS (0.43) | ALDH1A1POLBKMT2ASMN1; SMN2KDM4E | |
| Oxalic Acid SCHEMBL27753960 | 0.77 | FDPS (0.44) | ALDH1A1POLBKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL27698630 | 0.77 | ALDH1A1 (0.51) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| Acetic Acid SCHEMBL1662201 | 0.77 | ALDH1A1 (0.51) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| SCHEMBL950658 | 0.75 | ALDH1A1 (0.53) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| Oxalic Acid SCHEMBL27786842 | 0.74 | ALDH1A1 (0.42) | ALDH1A1POLBKMT2ATLR8HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576126-B2 | Platinum (II) complexes, preparation and use | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2009-08-18 | — | — | US | claimed |
| US-20070167643-A1 | Platinum (II) complexes, preparation and use | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2007-07-19 | — | — | US | claimed |
| EP-2011798-B1 | Preparation of platinum (II) complexes | PLATCO TECHNOLOGIES PROPRIETARY LTD (ZA) | 2011-06-29 | — | — | EP | disclosed |
| EP-2330110-A1 | Platinum(II) complexes, preparation and use | Platco Technologies (Proprietary) Limited (ZA) | 2011-06-08 | — | — | EP | disclosed |
| US-7956208-B2 | Preparation of platinum (II) complexes | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2011-06-07 | — | — | US | disclosed |
| US-7888523-B2 | Preparation of platinum(II) complexes | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2011-02-15 | — | — | US | disclosed |
| US-7888390-B2 | Preparation of platinum(II) complexes | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2011-02-15 | — | — | US | disclosed |
| US-20090312417-A1 | PLATINUM(II) COMPLEXES, PREPARATION AND USE | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2009-12-17 | — | — | US | disclosed |
| US-7576126-B2 | Platinum (II) complexes, preparation and use | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2009-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312417-A1 | PLATINUM(II) COMPLEXES, PREPARATION AND USE | PDCD5, ORC3, PDCD2L | ALDH1A1 3930/4885POLB 155/4885KMT2A 3504/4885 |
| US-20070167643-A1 | Platinum (II) complexes, preparation and use | PDCD5, ORC3, PDCD2L | ALDH1A1 3930/4885POLB 155/4885KMT2A 3504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.