SCHEMBL949946

SCHEMBL949946

CCCCn1ccnc1CSC

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
POLB P06746 1/20 0.56
KMT2A Q03164 1/20 0.56
TLR8 Q9NR97 2/20 0.49
TSHR P16473 2/20 0.38
CYP1A2 P05177 2/20 0.38
LMNA P02545 2/20 0.35
HTT P42858 1/20 0.33
ADORA2A P29274 1/20 0.33
KCNH2 Q12809 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
PKM P14618 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28768428 0.98 ALDH1A1 (0.54) ALDH1A1POLBKMT2ATLR8TSHR
SCHEMBL1155603 0.94 ALDH1A1 (0.50) ALDH1A1POLBKMT2ATLR8TSHR
Oxalic Acid SCHEMBL27753947 0.91 ALDH1A1 (0.47) ALDH1A1POLBKMT2ATLR8CYP1A2
Oxalic Acid SCHEMBL1155033 0.90 ALDH1A1 (0.46) ALDH1A1POLBKMT2ATLR8CYP1A2
SCHEMBL950658 0.83 ALDH1A1 (0.53) ALDH1A1POLBKMT2ATLR8TSHR
SCHEMBL27698630 0.82 ALDH1A1 (0.51) ALDH1A1POLBKMT2ATLR8TSHR
SCHEMBL6115119 0.82 ALDH1A1 (0.69) ALDH1A1POLBKMT2ATLR8TSHR
SCHEMBL9935809 0.82 ALDH1A1 (0.63) ALDH1A1POLBKMT2ATLR8LMNA
SCHEMBL329466 0.82 ALDH1A1 (0.63) ALDH1A1POLBKMT2ATLR8TSHR
SCHEMBL1049122 0.80 ALDH1A1 (0.61) ALDH1A1POLBKMT2ATLR8LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7888523-B2 Preparation of platinum(II) complexes PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2011-02-15 US claimed
US-7589225-B2 Preparation of platinum(II) complexes PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2009-09-15 US claimed
US-7576126-B2 Platinum (II) complexes, preparation and use PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2009-08-18 US claimed
EP-1789427-B1 PREPARATION OF PLATINUM(II) COMPLEXES PLATCO TECHNOLOGIES PROPRIETAR (ZA) 2009-05-20 EP claimed
US-20080064895-A1 Preparation of Platinum(II) Complexes PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2008-03-13 US claimed
CN-101018797-A Preparation of platinum (II) complexes PLATCO TECHNOLOGIES PROPRIETAR (ZA) 2007-08-15 CN claimed
US-20070167643-A1 Platinum (II) complexes, preparation and use PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2007-07-19 US claimed
EP-1789427-A1 PREPARATION OF PLATINUM(II) COMPLEXES Platco Technologies (Proprietary) Limited (ZA) 2007-05-30 EP claimed
EP-1704156-A1 PLATINUM(II) COMPLEXES, PREPARATION AND USE Platco Technologies (Proprietary) Limited (ZA) 2006-09-27 EP claimed
WO-2006024897-A1 PREPARATION OF PLATINUM(II) COMPLEXES PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2006-03-09 WO claimed
WO-2005051966-A1 PLATINUM(II) COMPLEXES, PREPARATION AND USE PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2005-06-09 WO claimed
EP-2011798-B1 Preparation of platinum (II) complexes PLATCO TECHNOLOGIES PROPRIETARY LTD (ZA) 2011-06-29 EP disclosed
EP-2330110-A1 Platinum(II) complexes, preparation and use Platco Technologies (Proprietary) Limited (ZA) 2011-06-08 EP disclosed
US-7956208-B2 Preparation of platinum (II) complexes PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2011-06-07 US disclosed
US-7888390-B2 Preparation of platinum(II) complexes PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2011-02-15 US disclosed
US-20070167643-A1 Platinum (II) complexes, preparation and use PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2007-07-19 US disclosed
EP-1789427-A1 PREPARATION OF PLATINUM(II) COMPLEXES Platco Technologies (Proprietary) Limited (ZA) 2007-05-30 EP disclosed
EP-1704156-A1 PLATINUM(II) COMPLEXES, PREPARATION AND USE Platco Technologies (Proprietary) Limited (ZA) 2006-09-27 EP disclosed
WO-2006024897-A1 PREPARATION OF PLATINUM(II) COMPLEXES PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2006-03-09 WO disclosed
WO-2005051966-A1 PLATINUM(II) COMPLEXES, PREPARATION AND USE PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2005-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070167643-A1 Platinum (II) complexes, preparation and use PDCD5, ORC3, PDCD2L ALDH1A1 3930/4885POLB 155/4885KMT2A 3504/4885
US-20080064895-A1 Preparation of Platinum(II) Complexes SLCO4C1, SLC10A6, OTC ALDH1A1 3885/4885POLB 233/4885KMT2A 2943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.