Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937852 | 0.84 | MAPT (0.43) | BRD4ERN1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL28937905 | 0.84 | KMT2A (0.47) | BRD4ERN1KMT2ATP53MAPT | |
| SCHEMBL11550337 | 0.83 | BRD4 (0.59) | BRD4ADORA2BADORA2AERN1ALDH1A1 | |
| SCHEMBL28937901 | 0.81 | ERN1 (0.49) | BRD4ADORA2BERN1ALDH1A1KMT2A | |
| SCHEMBL28963435 | 0.80 | TDP2 (0.43) | ADORA2AERN1BRD9TDP2TSHR | |
| SCHEMBL28937897 | 0.78 | ADORA2B (0.48) | ADORA2BERN1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL10566304 | 0.74 | ERN1 (0.59) | BRD4ERN1L3MBTL1KMT2ABRD9 | |
| SCHEMBL21052803 | 0.71 | BRD4 (0.39) | BRD4ERN1ALDH1A1LMNABRD9 | |
| SCHEMBL28937879 | 0.71 | BRD4 (0.45) | BRD4ERN1ALDH1A1USP2TSHR | |
| SCHEMBL28937854 | 0.71 | BRD4 (0.42) | BRD4ERN1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611816-A | Method for efficiently preparing 5-aryl (hetero) ring modified uracil derivative | 中国科学院化学研究所 | 2023-01-17 | — | — | CN | disclosed |