Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25C | P30307 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550539 | 0.82 | LCK (0.39) | BACE1KMT2ASLC6A4 | |
| SCHEMBL11551283 | 0.79 | BRD4 (0.44) | LMNABRD4METALDH1A1NPSR1 | |
| SCHEMBL11548893 | 0.78 | BRD4 (0.42) | BRD4RAB9ABACE1ALDH1A1KMT2A | |
| SCHEMBL11553718 | 0.69 | CYP2A6 (0.35) | BRD4RAB9ABACE1ALDH1A1KMT2A | |
| Biphenyl SCHEMBL7217541 | 0.69 | ALDH1A1 (0.45) | ALDH1A1NPSR1KMT2AHPGDTSHR | |
| SCHEMBL10396790 | 0.68 | PTGS2 (0.40) | METALDH1A1CDC25ACDC25CSLC6A4 | |
| SCHEMBL11554249 | 0.67 | BACE1 (0.41) | BRD4RAB9ABACE1ALDH1A1KMT2A | |
| SCHEMBL11848776 | 0.66 | MAPK14 (0.44) | ALDH1A1KMT2AMAPK1 | |
| SCHEMBL12276971 | 0.64 | NPC1 (0.45) | RAB9ANPSR1KMT2ACYP2A6MAPT | |
| Biphenyl SCHEMBL27656690 | 0.62 | ALDH1A1 (0.69) | ALDH1A1SLC6A4MAPTHSD17B10BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |