Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11434948 | 0.84 | PGR (0.41) | NPC1ALOX12RAB9AHSD17B10ALDH1A1 | |
| SCHEMBL11434674 | 0.84 | GAA (0.42) | NPC1RAB9AALDH1A1HPGDKMT2A | |
| SCHEMBL11551514 | 0.83 | PTGS2 (0.62) | — | |
| SCHEMBL11441313 | 0.83 | PTGS2 (0.43) | BRD4ALDH1A1HPGDKDM4E | |
| SCHEMBL11549660 | 0.82 | BRD4 (0.34) | BRD4HSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL11441308 | 0.82 | SMN1; SMN2 (0.35) | BRD4NPC1ALOX12RAB9ATDP1 | |
| SCHEMBL11175165 | 0.80 | ADORA2A (0.43) | NPC1RAB9AHSD17B10ALDH1A1HPGD | |
| SCHEMBL11554691 | 0.80 | PPARA (0.36) | BRD4KMT2ASMN1; SMN2 | |
| SCHEMBL11437913 | 0.79 | BRD4 (0.30) | BRD4KMT2A | |
| SCHEMBL11550647 | 0.78 | LMNA (0.36) | BRD4RAB9ABACE1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |