Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | CASP1 | P29466 | 3/20 | 0.55 |
| ▸ | CASP7 | P55210 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10472254 | 0.92 | KDM4E (0.72) | ADORA3KDM4EMAPTRAB9AHSD17B10 | |
| SCHEMBL10471694 | 0.88 | KDM4E (0.68) | ADORA3KDM4EMAPTRAB9AHSD17B10 | |
| SCHEMBL15266926 | 0.81 | ADORA3 (0.79) | ADORA3KDM4EMAPTRAB9AHSD17B10 | |
| SCHEMBL1664667 | 0.81 | ADORA3 (1.00) | ADORA3KDM4EMAPTRAB9AHSD17B10 | |
| SCHEMBL4683758 | 0.81 | KDM4E (1.00) | KDM4EMAPTRAB9AHSD17B10ALDH1A1 | |
| Chrysin Diacetate SCHEMBL15263635 | 0.79 | KDM4E (0.78) | ADORA3KDM4EMAPTRAB9AHSD17B10 | |
| SCHEMBL5076327 | 0.79 | KDM4E (0.61) | ADORA3KDM4EMAPTRAB9AHSD17B10 | |
| SCHEMBL8581726 | 0.78 | ALDH1A1 (0.65) | ADORA3KDM4EMAPTRAB9AHSD17B10 | |
| SCHEMBL7085863 | 0.76 | KDM4E (0.54) | ADORA3KDM4EMAPTRAB9AHSD17B10 | |
| SCHEMBL28514417 | 0.74 | ALDH1A1 (0.63) | KDM4EMAPTHSD17B10ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277595-A2 | Compounds for immunopotentiation | Novartis Vaccines and Diagnostics, Inc. (US) | 2011-01-26 | — | — | EP | disclosed |
| US-20100226931-A1 | Compounds for immunopotentiation | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2010-09-09 | — | — | US | disclosed |
| US-20100226931-A1 | Compounds for immunopotentiation | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2010-09-09 | — | — | US | disclosed |
| US-4166862-A | WEIGHT-GAIN PROMOTERS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1979-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100226931-A1 | Compounds for immunopotentiation | LY96, ICOS, PDCD1 | ADORA3 1365/4885KDM4E 558/4885MAPT 3668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.