Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | GLA | P06280 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | CASP1 | P29466 | 4/20 | 0.61 |
| ▸ | CASP7 | P55210 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10472254 | 0.80 | KDM4E (0.72) | KDM4EMAPTHSD17B10ALDH1A1GLA | |
| SCHEMBL11550658 | 0.79 | ADORA3 (0.68) | KDM4EMAPTHSD17B10ALDH1A1GLA | |
| SCHEMBL10471694 | 0.77 | KDM4E (0.68) | KDM4EMAPTHSD17B10ALDH1A1GLA | |
| SCHEMBL12325885 | 0.74 | KDM4E (0.59) | KDM4EMAPTHSD17B10ALDH1A1GLA | |
| SCHEMBL20581611 | 0.73 | ADORA3 (0.78) | KDM4EMAPTHSD17B10ALDH1A1GLA | |
| Kaempferol Tetraacetate SCHEMBL10379364 | 0.72 | ADORA3 (0.84) | KDM4EMAPTHSD17B10ALDH1A1GLA | |
| SCHEMBL9019344 | 0.72 | ADORA3 (0.62) | KDM4EMAPTHSD17B10ALDH1A1GLA | |
| SCHEMBL10339765 | 0.71 | ABCB1 (0.50) | KDM4EMAPTHSD17B10ALDH1A1GAA | |
| SCHEMBL17653939 | 0.71 | ADORA3 (0.71) | KDM4EMAPTHSD17B10ALDH1A1GLA | |
| SCHEMBL1664667 | 0.71 | ADORA3 (1.00) | KDM4EMAPTHSD17B10ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104230868-B | A kind of chemical preparation process of compound 2-methyl-5,7-dihydroxyl chromone | SYNYOO NEW MATERIALS CO., LTD. (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-104230868-A | Chemical preparation method of compound 2-methyl-5,7-dihydroxy chromone | GUANGDONG SYNYOO NEW MATERIALS COMPANY LTD | 2014-12-24 | — | — | CN | claimed |
| JP-1031719-A | — | — | None | — | — | JP | disclosed |
| CN-104230868-B | A kind of chemical preparation process of compound 2-methyl-5,7-dihydroxyl chromone | SYNYOO NEW MATERIALS CO., LTD. (CN) | 2016-04-27 | — | — | CN | disclosed |
| CN-104230868-B | A kind of chemical preparation process of compound 2-methyl-5,7-dihydroxyl chromone | SYNYOO NEW MATERIALS CO., LTD. (CN) | 2016-04-27 | — | — | CN | disclosed |
| US-9044409-B2 | Use of chromen-4-one derivatives | MERCK PATENT GMBH (DE) | 2015-06-02 | — | — | US | disclosed |
| US-9044409-B2 | Use of chromen-4-one derivatives | MERCK PATENT GMBH (DE) | 2015-06-02 | — | — | US | disclosed |
| US-9044409-B2 | Use of chromen-4-one derivatives | MERCK PATENT GMBH (DE) | 2015-06-02 | — | — | US | disclosed |
| CN-104230868-A | Chemical preparation method of compound 2-methyl-5,7-dihydroxy chromone | GUANGDONG SYNYOO NEW MATERIALS COMPANY LTD | 2014-12-24 | — | — | CN | disclosed |
| CN-104230868-A | Chemical preparation method of compound 2-methyl-5,7-dihydroxy chromone | GUANGDONG SYNYOO NEW MATERIALS COMPANY LTD | 2014-12-24 | — | — | CN | disclosed |
| EP-1508327-B1 | Use of 5,7-dihydroxy-2-methylchromen-4-on for the care of the skin | MERCK PATENT GMBH (DE) | 2014-05-07 | — | — | EP | disclosed |
| US-20070191305-A1 | Chromone complexes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2007-08-16 | — | — | US | disclosed |
| US-20060292093-A1 | Chromen-4-one derivatives | MERCK PATENT GMBH (DE) | 2006-12-28 | — | — | US | disclosed |
| EP-1732913-A1 | CHROMONE COMPLEXES | MERCK PATENT GmbH (DE) | 2006-12-20 | — | — | EP | disclosed |
| EP-1656364-A1 | CHROMEN-4-ONE DERIVATIVES | MERCK PATENT GmbH (DE) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005097772-A1 | CHROMONE COMPLEXES | MERCK PATENT GMBH (DE) | 2005-10-20 | — | — | WO | disclosed |
| WO-2005019197-A1 | CHROMEN-4-ONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2005-03-03 | — | — | WO | disclosed |
| US-20050043398-A1 | Use of chromen-4-one derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2005-02-24 | — | — | US | disclosed |
| EP-1508327-A1 | Use of chromen-4-one derivatives for the care of skin and hair | MERCK PATENT GmbH (DE) | 2005-02-23 | — | — | EP | disclosed |
| JP-S6431719-A | ANTIALLERGIC AGENT | TSUMURA & CO | 1989-02-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191305-A1 | Chromone complexes | SCO2, CDYL, CYCS | KDM4E 2073/4885MAPT 2017/4885HSD17B10 264/4885 |
| US-20050043398-A1 | Use of chromen-4-one derivatives | CYP8B1, CYP7B1, CYP2R1 | KDM4E 1606/4885MAPT 4649/4885HSD17B10 178/4885 |
| US-20060292093-A1 | Chromen-4-one derivatives | TYR, XPA, CYP19A1 | KDM4E 1205/4885MAPT 2375/4885HSD17B10 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.