Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 7/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547629 | 0.85 | ATM (0.53) | ADRB3ADRB1ADRB2ATMCYP1A2 | |
| SCHEMBL11545209 | 0.85 | ATM (0.53) | ADRB3ADRB1ADRB2ATMCYP1A2 | |
| SCHEMBL11548208 | 0.80 | ATM (0.53) | ADRB3ADRB1ADRB2ATMCYP1A2 | |
| SCHEMBL11554362 | 0.79 | KDM4E (0.49) | ADRB3ADRB1ADRB2ATMMEN1 | |
| SCHEMBL10714000 | 0.79 | ADRB2 (0.58) | ADRB3ADRB1ADRB2ATMCYP1A2 | |
| SCHEMBL11547450 | 0.78 | ATM (0.48) | ADRB3ADRB1ADRB2ATMCYP1A2 | |
| SCHEMBL11550521 | 0.76 | KDM4E (0.47) | ADRB3ADRB1ADRB2ATMCYP1A2 | |
| SCHEMBL11259392 | 0.74 | ADRB3 (0.50) | ADRB3ADRB1ADRB2ATMCYP1A2 | |
| SCHEMBL10714478 | 0.73 | ADRB2 (0.61) | ADRB3ADRB1ADRB2ATMCYP1A2 | |
| SCHEMBL11549370 | 0.73 | ABCB1 (0.46) | ADRB3ADRB1ADRB2CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139623-A | HYPOTENSIVE AGENTS | C-G CORP. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4027027-A | BETA-RECEPTOR-BLOCKERS, HYPOTENSIVES AND VALODILATORS; FOR TREATING ARRYTHMIAS AND ANGINA PECTORIS | CIBA-GEIGY CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |