SCHEMBL11550868

SCHEMBL11550868

CCc1ccccc1-c1ccccc1N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
CSNK2A2 P19784 1/20 0.47
CSNK2B P67870 1/20 0.47
CSNK2A1 P68400 1/20 0.47
CSNK2A3 Q8NEV1 1/20 0.47
HSD17B10 Q99714 1/20 0.44
CYP2D6 P10635 1/20 0.44
DHFR P00374 1/20 0.44
RECQL P46063 1/20 0.41
KCNN4 O15554 1/20 0.40
TLR8 Q9NR97 1/20 0.40
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.40
KMT2A Q03164 1/20 0.40
GABRA1 P14867 2/20 0.39
GABRB2 P47870 2/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
CASP1 P29466 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27471913 0.98 ALDH1A1 (0.56) ALDH1A1L3MBTL1CSNK2A2CSNK2BCSNK2A1
SCHEMBL28493009 0.85 CSNK2A2 (0.44) ALDH1A1L3MBTL1CSNK2A2CSNK2BCSNK2A1
SCHEMBL198461 0.85 CSNK2A2 (0.52) ALDH1A1L3MBTL1CSNK2A2CSNK2BCSNK2A1
SCHEMBL1647071 0.84 ALDH1A1 (0.50) ALDH1A1L3MBTL1CSNK2A2CSNK2BCSNK2A1
SCHEMBL1646441 0.84 ALDH1A1 (0.50) ALDH1A1L3MBTL1CSNK2A2CSNK2BCSNK2A1
SCHEMBL22212975 0.84 CSNK2A2 (0.42) ALDH1A1L3MBTL1CSNK2A2CSNK2BCSNK2A1
SCHEMBL11382359 0.83 CSNK2A2 (0.50) ALDH1A1L3MBTL1CSNK2A2CSNK2BCSNK2A1
Ethane SCHEMBL3687850 0.83 CSNK2A2 (0.50) ALDH1A1L3MBTL1CSNK2A2CSNK2BCSNK2A1
SCHEMBL2776956 0.83 CSNK2A2 (0.50) ALDH1A1L3MBTL1CSNK2A2CSNK2BCSNK2A1
SCHEMBL29565534 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3762387-B1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-12 EP disclosed
US-10364226-B2 Pyridazinone compounds and uses thereof ALIOS BIOPHARMA, INC. (US) 2019-07-30 US disclosed
EP-2993215-B1 Azabenzimidazo[2,1-a]benzimidazoles for electronic applications IDEMITSU KOSAN CO (JP) 2019-06-19 EP disclosed
EP-3030549-B1 PYRIDAZINONE COMPOUNDS AND USES THEREOF ALIOS BIOPHARMA INC (US) 2019-02-20 EP disclosed
EP-2982676-B1 Benzimidazo[2,1-B]benzoxazoles for electronic applications IDEMITSU KOSAN CO (JP) 2018-04-11 EP disclosed
US-20160221963-A1 PYRIDAZINONE COMPOUNDS AND USES THEREOF Janssen Pharmaceuticals, Inc. 2016-08-04 US disclosed
EP-3030549-A1 PYRIDAZINONE COMPOUNDS AND USES THEREOF Alios Biopharma, Inc. (US) 2016-06-15 EP disclosed
WO-2015038660-A1 PYRIDAZINONE COMPOUNDS AND USES THEREOF ALIOS BIOPHARMA, INC. (US) 2015-03-19 WO disclosed
US-4172081-A Benzotriazole ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-10-23 US disclosed
US-4116929-A POLYESTERS EASTMAN KODAK COMPANY (US) 1978-09-26 US disclosed
US-4088734-A WASHING GASES WITH AQUEOUS ALKALINE SOLUTION OF ZINC OR LEAD COMPOUND AND/OR ANTHRAQUINONE SULFONIC ACID INSTITUT FRANCAIS DU PETROLE (FR) 1978-05-09 US disclosed
US-4017508-A POLYMERS EASTMAN KODAK COMPANY (US) 1977-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160221963-A1 PYRIDAZINONE COMPOUNDS AND USES THEREOF PDXK, PNPO, PLPBP ALDH1A1 2151/4885L3MBTL1 3874/4885CSNK2A2 2659/4885
US-10364226-B2 Pyridazinone compounds and uses thereof PDXK, PNPO, PLPBP ALDH1A1 2151/4885L3MBTL1 3874/4885CSNK2A2 2659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.