Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HBB | P68871 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 7/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.35 |
| ▸ | POLG | P54098 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10649180 | 0.88 | MEN1 (0.63) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL9366802 | 0.88 | MEN1 (0.63) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL10481448 | 0.83 | KMT2A (0.46) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL9371648 | 0.83 | MEN1 (0.57) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL9426305 | 0.79 | MEN1 (0.54) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL7819447 | 0.78 | MEN1 (1.00) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL9116074 | 0.78 | MEN1 (0.40) | MEN1KMT2ATSHRHSD17B10HPRT1 | |
| SCHEMBL9575539 | 0.75 | MEN1 (0.48) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL11249941 | 0.74 | MEN1 (0.57) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL11244724 | 0.74 | MEN1 (0.57) | MEN1KMT2ATSHRHBBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146715-A | ANTIVIRAL AGENTS | BURROUGHS WELLCOME CO. (US) | 1979-03-27 | — | — | US | disclosed |