Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10997483 | 0.93 | TSHR (0.50) | MEN1KMT2ATSHRP2RX7ALDH1A1 | |
| SCHEMBL9366819 | 0.89 | MEN1 (0.56) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL12537333 | 0.86 | P2RX7 (0.50) | MEN1KMT2ATSHRP2RX7ALDH1A1 | |
| SCHEMBL9366802 | 0.85 | MEN1 (0.63) | MEN1KMT2ATSHRP2RX7ALDH1A1 | |
| SCHEMBL7448126 | 0.84 | MEN1 (0.53) | MEN1KMT2ATSHRP2RX7HBB | |
| SCHEMBL11242909 | 0.83 | P2RX7 (0.48) | MEN1KMT2ATSHRP2RX7ALDH1A1 | |
| SCHEMBL30496451 | 0.81 | P2RX7 (0.43) | MEN1KMT2ATSHRP2RX7ALDH1A1 | |
| SCHEMBL3267555 | 0.81 | P2RX7 (0.43) | MEN1KMT2ATSHRP2RX7ALDH1A1 | |
| SCHEMBL8306098 | 0.80 | P2RX7 (0.43) | TSHRP2RX7HBBPNPUSP2 | |
| SCHEMBL11249941 | 0.78 | MEN1 (0.57) | MEN1KMT2ATSHRALDH1A1HBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360522-A | VIRICIDES | BURROUGHS WELLCOME CO. (US) | 1982-11-23 | — | — | US | disclosed |
| US-4323573-A | VIRICIDES | BURROUGHS WELLCOME CO. (US) | 1982-04-06 | — | — | US | disclosed |
| US-4294831-A | ANTIVIRAL ACTIVITY | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | disclosed |
| US-4199574-A | Methods and compositions for treating viral infections and guanine acyclic nucleosides | BURROUGHS WELLCOME CO. (US) | 1980-04-22 | — | — | US | disclosed |
| US-4146715-A | ANTIVIRAL AGENTS | BURROUGHS WELLCOME CO. (US) | 1979-03-27 | — | — | US | disclosed |