Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | HBB | P68871 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550890 | 0.88 | MEN1 (0.64) | MEN1KMT2ATSHRACHEHBB | |
| SCHEMBL9575539 | 0.87 | MEN1 (0.48) | MEN1KMT2ATSHRACHEHBB | |
| SCHEMBL10649180 | 0.87 | MEN1 (0.63) | MEN1KMT2ATSHRACHEHBB | |
| SCHEMBL11244724 | 0.85 | MEN1 (0.57) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL9366819 | 0.84 | MEN1 (0.56) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL10405793 | 0.83 | ACHE (0.44) | MEN1KMT2ATSHRACHEBLM | |
| SCHEMBL8896639 | 0.82 | ACHE (0.44) | MEN1KMT2ATSHRACHEHBB | |
| SCHEMBL8713036 | 0.80 | ACHE (0.47) | MEN1KMT2ATSHRACHEP2RX7 | |
| SCHEMBL9371648 | 0.80 | MEN1 (0.57) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL7448126 | 0.79 | MEN1 (0.53) | MEN1KMT2ATSHRHBBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289992-B1 | Process for preparing purine derivates | KEMIJSKI INST (SI) | 1994-04-27 | — | — | EP | disclosed |
| EP-0564006-A2 | Process for preparing purine derivatives and novel purine derivatives | KRKA, tovarna zdravil, n.sol.o (YU) | 1993-10-06 | — | — | EP | disclosed |
| EP-0289992-A2 | Process for preparing purine derivates | KEMIJSKI INSTITUT (SI) | 1988-11-09 | — | — | EP | disclosed |