Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680034 | 0.88 | F2 (0.53) | HSP90AA1F2APPESR2 | |
| SCHEMBL11577115 | 0.80 | TUBB4A (0.49) | ATMCNR1CNR2L3MBTL1TDP1 | |
| SCHEMBL7506626 | 0.79 | PTPN1 (0.81) | PTPN1HSP90AA1 | |
| SCHEMBL6172878 | 0.78 | ESR1 (0.66) | F2ESR2 | |
| SCHEMBL7411720 | 0.78 | F2 (0.75) | CNR1TDP1MEN1KMT2AF2 | |
| SCHEMBL6171204 | 0.78 | F2 (0.75) | CNR1TDP1MEN1KMT2AF2 | |
| SCHEMBL8012539 | 0.78 | F2 (0.73) | CNR1TDP1MEN1KMT2AF2 | |
| SCHEMBL7972975 | 0.77 | F2 (0.63) | PTPN1F2ESR2MAPK1 | |
| SCHEMBL20932951 | 0.77 | LTA4H (0.50) | ATMCNR2L3MBTL1TDP1MEN1 | |
| SCHEMBL6171704 | 0.76 | F2 (0.75) | F2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133814-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |