Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11551750 | 0.90 | BRD4 (0.47) | BRD4CA12CA1CA2CA9 | |
| SCHEMBL11549547 | 0.86 | BRD4 (0.44) | BRD4CA12CA2CA9POLB | |
| SCHEMBL11550515 | 0.86 | BRD4 (0.41) | BRD4POLBMEN1KMT2AADORA3 | |
| SCHEMBL11555425 | 0.81 | BRD4 (0.41) | BRD4ADORA3TP53MAPTHPGD | |
| SCHEMBL11428354 | 0.81 | BRD4 (0.41) | BRD4TP53MAPT | |
| SCHEMBL11428176 | 0.81 | HSD11B1 (0.45) | BRD4POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11552820 | 0.79 | BRD4 (0.46) | BRD4POLBMEN1KMT2ANPC1 | |
| SCHEMBL11426570 | 0.78 | BRD4 (0.40) | BRD4POLBMEN1KMT2AMAPT | |
| SCHEMBL11426898 | 0.78 | EGFR (0.43) | BRD4CA12CA9MEN1KMT2A | |
| SCHEMBL11437271 | 0.77 | MAOB (0.43) | BRD4CA12CA9POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |