Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 5/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549248 | 0.91 | GUSB (0.56) | GUSBHDAC6POLBMEN1TSHR | |
| SCHEMBL11375677 | 0.86 | PDE5A (0.54) | GUSBPOLBMEN1KMT2APDE5A | |
| SCHEMBL11549471 | 0.86 | GUSB (0.53) | GUSBHDAC6POLBMEN1TSHR | |
| SCHEMBL11382413 | 0.85 | GUSB (0.59) | GUSBHDAC6POLBMEN1TSHR | |
| SCHEMBL11552075 | 0.84 | GUSB (0.47) | GUSBHDAC6POLBMEN1KMT2A | |
| SCHEMBL11551096 | 0.83 | GUSB (0.48) | GUSBHDAC6POLBMEN1KMT2A | |
| SCHEMBL11549992 | 0.82 | POLB (0.48) | GUSBPOLBMEN1KMT2ANPC1 | |
| SCHEMBL11554055 | 0.82 | GUSB (0.55) | GUSBPOLBTSHRPDE5ANPC1 | |
| SCHEMBL11554449 | 0.82 | GUSB (0.47) | GUSBHDAC6POLBMEN1KMT2A | |
| SCHEMBL11379676 | 0.82 | GUSB (0.51) | GUSBPOLBMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | claimed |
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | disclosed |