Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553427 | 0.82 | ALDH1A1 (0.50) | GAAPOLBHSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL1683212 | 0.80 | NQO1 (0.65) | NQO1HSD17B10ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8195554 | 0.77 | POLB (0.42) | GAAPOLBALOX15HSD17B10L3MBTL1 | |
| SCHEMBL13681552 | 0.76 | HPGD (0.44) | GAAHTTPOLBALOX15HSD17B10 | |
| SCHEMBL509575 | 0.74 | FFAR1 (0.48) | GAAHTTHSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL2781336 | 0.73 | SOD1 (0.39) | GAAPOLBHSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL27925496 | 0.73 | EGFR (0.39) | GAAPOLBHSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL3915652 | 0.73 | ALDH1A1 (0.42) | GAAHTTPOLBALOX15HSD17B10 | |
| SCHEMBL15334777 | 0.72 | POLB (0.39) | GAAHTTPOLBALOX15HSD17B10 | |
| SCHEMBL12311020 | 0.72 | POLB (0.46) | GAAHTTPOLBHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146647-A | PHENYLAMIDOXIMES, HYPOTENSIVE AGENTS | LABORATOIRE L. LAFON (FR) | 1979-03-27 | — | — | US | disclosed |