Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024496 | 0.87 | ADRB2 (0.62) | LMNATDP1ADRB2ADRB1CNR1 | |
| SCHEMBL8405103 | 0.84 | ALDH1A1 (0.51) | LMNATDP1ADRB2ADRB1CNR1 | |
| SCHEMBL8402101 | 0.84 | ALDH1A1 (0.51) | LMNATDP1ADRB2ADRB1CNR1 | |
| SCHEMBL4751700 | 0.81 | ALDH1A1 (0.54) | LMNATDP1ADRB2ADRB1CNR1 | |
| SCHEMBL27296585 | 0.78 | NPY5R (0.44) | LMNATDP1ADRB2ADRB1CNR1 | |
| SCHEMBL8405959 | 0.78 | NPY5R (0.44) | LMNATDP1ADRB2ADRB1CNR1 | |
| SCHEMBL8406380 | 0.78 | NPY5R (0.44) | LMNATDP1ADRB2ADRB1CNR1 | |
| SCHEMBL9452308 | 0.78 | TDP1 (0.49) | LMNATDP1ADRB2ADRB1KDM4E | |
| SCHEMBL27887827 | 0.77 | FFAR1 (0.51) | LMNATDP1ADRB2ADRB1CNR1 | |
| SCHEMBL11022591 | 0.77 | CYP4F2 (0.51) | ADRB2ADRB1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005142-A1 | Phenylpiperazine derivatives, process for their preparation, intermediates for this purpose and medicaments containing such phenylpiperazine derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-11-14 | — | — | EP | disclosed |