Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | BRS3 | P32247 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7971722 | 0.83 | BRS3 (0.43) | BRS3DAO | |
| Hydrochloric Acid SCHEMBL8131099 | 0.83 | BRS3 (0.43) | HPGDSAOC3CAPN1TAAR1BRS3 | |
| SCHEMBL7688678 | 0.82 | HPGDS (0.50) | HPGDSAOC3CAPN1TAAR1PDE10A | |
| Hydrochloric Acid SCHEMBL8130185 | 0.81 | BRS3 (0.43) | HPGDSTAAR1BRS3GAADAO | |
| Hydrochloric Acid SCHEMBL8196463 | 0.81 | HRH3 (0.42) | HPGDSAOC3TAAR1BRS3HRH3 | |
| Hydrochloric Acid SCHEMBL8124532 | 0.81 | BRS3 (0.47) | TAAR1BRS3DAOHRH1 | |
| SCHEMBL8957090 | 0.81 | HRH1 (0.62) | HPGDSAOC3CAPN1TAAR1PDE10A | |
| SCHEMBL9314265 | 0.80 | KEAP1 (0.50) | HPGDSAOC3CAPN1BRS3DAO | |
| SCHEMBL7468902 | 0.79 | HRH3 (0.48) | BRS3DAOHRH3 | |
| SCHEMBL7345076 | 0.78 | BRS3 (0.49) | HPGDSAOC3CAPN1TAAR1BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005528-A2 | Imidazole derivatives, their preparation and pharmaceutical compositions | Takeda Chemical Industries, Ltd. (JP) | 1979-11-28 | — | — | EP | disclosed |