Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | BRS3 | P32247 | 4/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314201 | 0.91 | HDAC3 (0.53) | KEAP1BRS3TBXAS1CYP1A2HPGDS | |
| SCHEMBL9314193 | 0.87 | HSD11B1 (0.48) | BRS3CYP1A2HPGDSAOC3CAPN1 | |
| SCHEMBL7345076 | 0.86 | BRS3 (0.49) | BRS3HPGDSAOC3CAPN1DAO | |
| Hydrochloric Acid SCHEMBL8368581 | 0.82 | BRS3 (0.52) | BRS3FFAR1TBXAS1FFAR4MMP2 | |
| SCHEMBL7688678 | 0.80 | HPGDS (0.50) | BRS3HPGDSAOC3CAPN1DAO | |
| SCHEMBL11552467 | 0.80 | HPGDS (0.50) | BRS3HPGDSAOC3CAPN1DAO | |
| SCHEMBL8957090 | 0.79 | HRH1 (0.62) | BRS3HPGDSAOC3CAPN1KDM4E | |
| SCHEMBL8957140 | 0.78 | SLC7A5 (0.54) | BRS3HSD17B10HPGDSAOC3 | |
| SCHEMBL5201259 | 0.77 | PDE9A (0.40) | BRS3CYP1A2CYP2C9HSD17B10CHRM1 | |
| SCHEMBL7846648 | 0.77 | MMP2 (0.51) | BRS3HSD17B10HPGDSAOC3CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589975-A1 | NEW SELECTIVE AROMATASE INHIBITING 4(5)-IMIDAZOLES | ORION-YHTYMÀ OY (FI) | 1994-04-06 | — | — | EP | disclosed |
| WO-1992022537-A1 | NEW SELECTIVE AROMATASE INHIBITING 4(5)-IMIDAZOLES | Orion-Yhtymä Oy (FI) | 1992-12-23 | — | — | WO | disclosed |
| EP-0403158-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |