Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553868 | 0.81 | TSHR (0.60) | TSHRCYP3A4MAPK1TDP1ALDH1A1 | |
| SCHEMBL29707579 | 0.79 | IDO1 (0.47) | NT5EMAPTKDM1A | |
| SCHEMBL264729 | 0.79 | IDO1 (0.47) | NT5EMAPTKDM1A | |
| SCHEMBL12791524 | 0.79 | PTGDR2 (0.42) | ALDH1A1NT5EMAPTHIF1APYCR1 | |
| SCHEMBL11552544 | 0.78 | HSP90AA1 (0.41) | TSHRCYP3A4MAPK1TDP1ALDH1A1 | |
| SCHEMBL3234438 | 0.76 | ALDH1A1 (0.42) | MAPK1ALDH1A1NT5EMAPTALOX15 | |
| SCHEMBL31342658 | 0.76 | NT5E (0.40) | ALDH1A1NT5EMAPTKDM1A | |
| SCHEMBL5779231 | 0.76 | NT5E (0.40) | ALDH1A1NT5EMAPTKDM1A | |
| SCHEMBL7943012 | 0.75 | TSHR (0.65) | TSHRCYP3A4MAPK1TDP1ALDH1A1 | |
| SCHEMBL30965839 | 0.75 | TSHR (0.65) | TSHRCYP3A4MAPK1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111620778-A | Preparation method of 5-bromo-2-chlorobenzoic acid | 吴赣药业（苏州）有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-119504465-A | Preparation method of 3-amino-2-fluorobenzoyl halide | 帕潘纳(北京)科技有限公司 | 2025-02-25 | — | — | CN | disclosed |
| EP-4389733-A1 | METHOD FOR PREPARING 5-BROMO-2-CHLORO-BENZOIC ACID AS RAW MATERIAL IN HYPOGLYCEMIC DRUG SYNTHESIS | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2024-06-26 | — | — | EP | disclosed |
| CN-113912487-B | Synthesis method of 2, 5-dihalobenzoic acid | 山东研峰新材料科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-113912487-A | Synthesis method of 2, 5-bis-halogenated benzoic acid | 山东研峰新材料科技有限公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-108250060-B | Synthesis method of 5-bromo-2-chlorobenzoic acid | 江苏尚莱特医药化工材料有限公司 | 2021-10-15 | — | — | CN | disclosed |
| CN-111620778-A | Preparation method of 5-bromo-2-chlorobenzoic acid | 吴赣药业（苏州）有限公司 | 2020-09-04 | — | — | CN | disclosed |
| CN-111620778-A | Preparation method of 5-bromo-2-chlorobenzoic acid | 吴赣药业（苏州）有限公司 | 2020-09-04 | — | — | CN | disclosed |
| CN-105622382-A | Synthesis method of 5-bromo-2-chloro benzoic acid | SUZHOU TIANMA SPECIALTY CHEMICALS CO LTD | 2016-06-01 | — | — | CN | disclosed |