Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | PRMT7 | Q9NVM4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11552117 | 0.81 | TTR (0.38) | TTRNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL17559568 | 0.79 | KDM4E (0.53) | TTRNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL11554941 | 0.77 | SIGMAR1 (0.47) | MEN1ALDH1A1TP53HPGDKMT2A | |
| SCHEMBL11810130 | 0.75 | KDM4E (0.48) | KDM4EALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL11800787 | 0.75 | ABCC4 (0.35) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL11550231 | 0.74 | TTR (0.40) | TTRNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL11838004 | 0.74 | TTR (0.45) | TTRNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL15803431 | 0.73 | NPC1 (0.41) | TTRNPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL11550016 | 0.73 | ALDH1A1 (0.54) | TTRNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL11228973 | 0.72 | ALDH1A1 (0.45) | NPC1RAB9AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146624-A | METHOD OF TREATING VIRUSES WITH BIS-BASIC KETONES OF DIBENZOFURAN | RICHARDSON-MERRELL INC. (US) | 1979-03-27 | — | — | US | disclosed |