Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | DBH | P09172 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11869257 | 0.81 | PTGS2 (0.36) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL19253135 | 0.81 | KDM4E (0.49) | ABCC4PTGS1RAB9AMAPTNPC1 | |
| SCHEMBL11800382 | 0.80 | CHRM2 (0.45) | MAPTHPGDALDH1A1KDM4E | |
| SCHEMBL17559555 | 0.78 | KDM4E (0.44) | ABCC4PTGS1RAB9AMAPTNPC1 | |
| SCHEMBL6836837 | 0.76 | CTNNB1 (0.43) | HPGDALDH1A1 | |
| SCHEMBL11797647 | 0.76 | HPGD (0.41) | TAS1R3TAS1R1HPGDALDH1A1KDM4E | |
| SCHEMBL11677033 | 0.76 | MAPT (0.42) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL11553445 | 0.75 | TTR (0.39) | RAB9ANPC1HTR1BHPGDALDH1A1 | |
| SCHEMBL11750545 | 0.74 | ALDH1A1 (0.49) | MAPTHPGDALDH1A1KDM4E | |
| SCHEMBL11733551 | 0.74 | CTNNB1 (0.42) | RAB9AMAPTNPC1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957989-A | ADMINISTERING | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |